RRP8

Across TCGA patient cohorts, RRP8 RNA expression is significantly associated with the mutation status of many other genes, with 12,895 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RRP8-associated genes across cancer lineages are HRAS, TP53, and VCAN. Each is linked with RRP8 in more than 2 cancer types. Because this analysis shows association rather than direction, both RRP8-to-partner and partner-to-RRP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HRAS grouped by RRP8-low versus RRP8-high in THCA.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRP8→partner) and Y-score (partner→RRP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	HRAS →	+4.051	+0.473	<.001	<.001	3	3
BRCA	TP53 →	-1.224	-0.283	<.001	<.001	3	3
BLCA	VCAN →	+3.992	+0.242	<.001	.003	3	3
LUSC	ANO3 →	+2.275	+0.225	.005	.005	3	3
LUSC	CNGB3 →	+3.035	+0.252	<.001	<.001	3	3
UCEC	MXRA5 →	+1.623	+0.349	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,895 associations by consensus.

HRAS by RRP8 expression — THCA

Explore this box plot interactively →