RRP8

Across TCGA patient cohorts, RRP8 protein abundance is significantly associated with the RNA expression of many other genes, with 13,508 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RRP8-associated genes across cancer lineages are RPS21, NAT10, and ABCA6. Each is linked with RRP8 in more than 5 cancer types. Because this analysis shows association rather than direction, both RRP8-to-partner and partner-to-RRP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RRP8 versus RPS21 in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRP8→partner) and Y-score (partner→RRP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS21 →	+0.970	+0.205	<.001	<.001	3	6
LSCC	NAT10 →	+0.449	+0.282	.003	<.001	3	6
BRCA	ABCA6 →	-0.661	-0.287	.003	.001	3	6
HNSC	MEF2C →	-0.714	-0.148	<.001	.001	3	6
UCEC	RPLP2 →	+1.506	+0.213	.001	<.001	3	5
UCEC	RPLP0 →	+1.443	+0.189	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,508 associations by consensus.

RRP8 vs RPS21 — UCEC

Explore this scatter interactively →