RRP8

Across TCGA cell cohorts, RRP8 mutation is significantly associated with the mutation status of many other genes, with 1,241 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RRP8-associated genes across cancer lineages are AGPAT2, CORO7, and IFITM1. Each is linked with RRP8 in more than 2 cancer types. Because this analysis shows association rather than direction, both RRP8-to-partner and partner-to-RRP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AGPAT2 grouped by RRP8-low versus RRP8-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRP8→partner) and Y-score (partner→RRP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	AGPAT2 →	+5.894	+5.321	.002	.002	1	3
BLOOD_Leukemia	CORO7 →	+3.672	+5.083	.001	.001	1	3
LARGE_INTESTINE	IFITM1 →	+4.523	+5.087	.006	.006	1	3
BLOOD_Leukemia	GGT1 →	+4.309	+4.560	.007	.007	1	2
BLOOD_Leukemia	SUSD6 →	+4.894	+4.894	.004	.004	1	2
LARGE_INTESTINE	SPEF1 →	+4.523	+5.087	.006	.006	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,241 associations by consensus.

AGPAT2 by RRP8 expression — BLOOD_Leukemia

Explore this box plot interactively →