Across TCGA patient cohorts, RRP7A mutation is significantly associated with the RNA expression of many other genes, with 461 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RRP7A-associated genes across cancer lineages are LDHBP3, COX6B1P7, and RNU6-494P. Each is linked with RRP7A in more than 2 cancer types. Because this analysis shows association rather than direction, both RRP7A-to-partner and partner-to-RRP7A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRP7A→partner) and Y-score (partner→RRP7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LDHBP3 →	+0.105	+4.070	.003	.009	3	3
COAD	COX6B1P7 →	+0.259	+4.070	<.001	.009	3	2
COAD	RNU6-494P →	+0.835	+3.067	<.001	.008	3	2
COAD	SOD1P2 →	+0.179	+3.730	<.001	.004	3	2
UCEC	RN7SL98P →	+0.173	+3.430	<.001	<.001	3	2
COAD	RNU6-666P →	+0.559	+5.412	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 461 associations by consensus.

Exploration

RRP7A survival (RNA) · tumor vs normal (RNA) · all RRP7A data types