RRP36

Across TCGA patient cohorts, RRP36 mutation is significantly associated with the RNA expression of many other genes, with 1,373 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RRP36-associated genes across cancer lineages are RNA5SP419, BTBD10, and PGAP2. Each is linked with RRP36 in more than 1 cancer types. Because this analysis shows association rather than direction, both RRP36-to-partner and partner-to-RRP36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by RRP36-low versus RRP36-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRP36→partner) and Y-score (partner→RRP36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.619	+2.202	<.001	.005	3	2
UCEC	BTBD10 →	+0.524	+3.491	.002	.002	3	1
UCEC	PGAP2 →	+0.439	+4.010	.004	<.001	3	1
UCEC	PTPRJ →	+0.831	+3.483	<.001	.002	3	1
UCEC	INTS4 →	+0.341	+2.939	.008	<.001	3	1
UCEC	EI24 →	+0.578	+4.000	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,373 associations by consensus.

RNA5SP419 by RRP36 expression — UCEC

Explore this box plot interactively →