RRP1B

Across TCGA patient cohorts, RRP1B mutation is significantly associated with the RNA expression of many other genes, with 2,591 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RRP1B-associated genes across cancer lineages are RNA5SP414, RNA5SP417, and EIF1AXP2. Each is linked with RRP1B in more than 2 cancer types. Because this analysis shows association rather than direction, both RRP1B-to-partner and partner-to-RRP1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP414 grouped by RRP1B-low versus RRP1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRP1B→partner) and Y-score (partner→RRP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP414 →	+0.568	+1.933	<.001	.009	3	3
UCEC	RNA5SP417 →	+0.575	+2.351	<.001	.001	3	3
SKCM	EIF1AXP2 →	+0.056	+2.623	.006	.008	3	3
SKCM	MOB1AP2 →	+0.019	+3.897	<.001	.009	3	3
BRCA	RNA5SP422 →	+0.865	+8.055	<.001	.007	3	2
BRCA	RNA5SP416 →	+0.725	+8.471	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,591 associations by consensus.

RNA5SP414 by RRP1B expression — UCEC

Explore this box plot interactively →