RRP12

Across TCGA cell cohorts, RRP12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,761 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RRP12-associated GO terms across cancer lineages are Positive regulation of rRNA processing, Nucleolar large rRNA transcription by RNA polymerase I, and rRNA metabolic process. Each is linked with RRP12 in more than 17 cancer types. Because this analysis shows association rather than direction, both RRP12-to-partner and partner-to-RRP12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of rRNA processing grouped by RRP12-low versus RRP12-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RRP12→partner) and Y-score (partner→RRP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of rRNA processing →	+0.124	+0.902	<.001	<.001	3	18
BONE	Nucleolar large rRNA transcription by RNA polymerase I →	+0.116	+0.950	.001	<.001	3	18
LUNG_SCLC	rRNA metabolic process →	+0.115	+0.852	<.001	<.001	3	17
BONE	Ribosome biogenesis →	+0.139	+1.238	<.001	<.001	3	17
BONE	Ribosomal small subunit biogenesis →	+0.133	+1.185	<.001	<.001	3	17
SOFT_TISSUE	Transcription initiation at RNA polymerase I promoter →	+0.112	+1.039	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,761 associations by consensus.

Positive regulation of rRNA processing by RRP12 expression — OVARY

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