RRP12

Across TCGA pan-cancer cohorts, RRP12 RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of RRP12’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RRP12 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RRP12 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

STAD, COAD, and KIRP are the cancer types where RRP12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RRP12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	Male	II,III,IV	+1.653	<.001	11	view →
COAD	Female	All	+1.619	<.001	11	view →
KIRP	Female	II,III,IV	+1.173	<.001	11	view →
LIHC	Male	II,III,IV	+1.680	<.001	9	view →
LUAD	All	III,IV	+1.147	<.001	9	view →
KIRC	Female	III,IV	+0.550	<.001	9	view →
HNSC	Male	All	+0.825	<.001	8	view →
UCEC	All	III,IV	+1.036	.001	6	view →
LUSC	Male	II,III,IV	+0.631	<.001	6	view →
BRCA	All	All	+0.599	<.001	6	view →
CHOL	Male	All	+2.710	<.001	5	view →
READ	All	All	+1.336	.002	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

RRP12–STAD

Open the STAD breakdown →