RRP12

Across TCGA cell cohorts, RRP12 mutation is significantly associated with the RNA expression of many other genes, with 1,049 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RRP12-associated genes across cancer lineages are AVP, SBF1, and IFT27. Each is linked with RRP12 in more than 1 cancer types. Because this analysis shows association rather than direction, both RRP12-to-partner and partner-to-RRP12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by RRP12-low versus RRP12-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRP12→partner) and Y-score (partner→RRP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	AVP →	+0.035	+4.734	<.001	.002	3	2
LARGE_INTESTINE	SBF1 →	+0.601	+3.502	.008	.001	3	2
LARGE_INTESTINE	IFT27 →	+0.746	+3.588	.006	<.001	3	2
LARGE_INTESTINE	CSPG5 →	+0.852	+3.588	<.001	<.001	3	2
LARGE_INTESTINE	SGSM1 →	+0.421	+2.624	.001	.003	3	2
BONE	FAM177B →	+0.025	+3.688	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,049 associations by consensus.

AVP by RRP12 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →