RRH

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RRH RNA expression is significantly associated with the go_rna of many other GO terms, with 2,175 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RRH-associated GO terms across cancer lineages are Regulation of chromosome condensation, Intraciliary anterograde transport, and DNA-templated DNA replication maintenance of fidelity. Each is linked with RRH in more than 8 cancer types. Because this analysis shows association rather than direction, both RRH-to-partner and partner-to-RRH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome condensation grouped by RRH-low versus RRH-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RRH→partner) and Y-score (partner→RRH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHRegulation of chromosome condensation →+0.142+0.091.002.00939
SOFT_TISSUEIntraciliary anterograde transport →+0.072+0.097.003.00238
LARGE_INTESTINEDNA-templated DNA replication maintenance of fidelity →+0.071+0.288<.001<.00138
LARGE_INTESTINEDouble-strand break repair →+0.043+0.245<.001<.00138
BLOOD_LymphomaConstitutive heterochromatin formation →+0.061+0.083.001.00737
LARGE_INTESTINEReplication fork processing →+0.065+0.222<.001.00428
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,175 associations by consensus.

Regulation of chromosome condensation by RRH expression — STOMACH

Box plot of Regulation of chromosome condensation in RRH-low vs RRH-high samples in STOMACH.

Explore this box plot interactively →

Exploration