RREB1

Across TCGA patient cohorts, RREB1 protein abundance is significantly associated with the protein abundance of many other proteins, with 25,755 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RREB1-associated proteins across cancer lineages are RREB1_S36, SARM1, and RBM25. Each is linked with RREB1 in more than 8 cancer types. Because this analysis shows association rather than direction, both RREB1-to-partner and partner-to-RREB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RREB1 versus RREB1_S36 in GBM, with a Pearson correlation of 0.44.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RREB1→partner) and Y-score (partner→RREB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RREB1_S36 →	+0.655	+0.440	<.001	<.001	3	9
BRCA	SARM1 →	-0.632	-0.291	<.001	<.001	3	9
LUAD	RBM25 →	+0.217	+0.276	<.001	<.001	3	8
LSCC	RBBP6 →	+0.193	+0.211	<.001	<.001	3	8
LSCC	SRRM2 →	+0.236	+0.295	<.001	<.001	3	8
LSCC	KDM1A →	+0.323	+0.346	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,755 associations by consensus.

RREB1 vs RREB1_S36 — GBM

Explore this scatter interactively →