RREB1

Across TCGA cell cohorts, RREB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,400 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RREB1-associated GO terms across cancer lineages are Endosomal transport, Copper ion export, and Oocyte growth. Each is linked with RREB1 in more than 13 cancer types. Because this analysis shows association rather than direction, both RREB1-to-partner and partner-to-RREB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by RREB1-low versus RREB1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RREB1→partner) and Y-score (partner→RREB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Endosomal transport →	+0.057	+0.709	<.001	<.001	3	14
OVARY	Copper ion export →	-0.201	-0.850	<.001	.001	3	14
BONE	Oocyte growth →	+0.219	+1.024	.001	.002	3	14
SKIN	Positive regulation of TORC2 signaling →	+0.112	+0.709	<.001	<.001	3	14
LARGE_INTESTINE	Positive regulation of T-helper 17 cell lineage commitment →	+0.198	+0.908	<.001	<.001	3	14
STOMACH	Regulation of TORC2 signaling →	+0.114	+0.855	.003	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,400 associations by consensus.

Endosomal transport by RREB1 expression — SKIN

Explore this box plot interactively →