RRAGA

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RRAGA protein abundance is significantly associated with the RNA expression of many other genes, with 5,729 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RRAGA-associated genes across cancer lineages are PLIN2, CADM4, and RNU6-137P. Each is linked with RRAGA in more than 2 cancer types. Because this analysis shows association rather than direction, both RRAGA-to-partner and partner-to-RRAGA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RRAGA versus PLIN2 in GBM, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRAGA→partner) and Y-score (partner→RRAGA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPLIN2 →+1.642+0.549<.001<.00133
CCRCCCADM4 →-0.915-0.356.001<.00133
HNSCRNU6-137P →-1.147-0.318<.001<.00133
HNSCMYB →-0.818-0.210.002.00132
HNSCMIR215 →-0.865-0.204<.001.00132
GBMMRPL3 →-0.393-0.518.008.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,729 associations by consensus.

RRAGA vs PLIN2 — GBM

Per-sample scatter of RRAGA vs PLIN2 in GBM (Pearson r = 0.45).

Explore this scatter interactively →

Exploration