RRAGA

Across TCGA patient cohorts, RRAGA mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RRAGA-associated genes across cancer lineages are Adipocytes, Endothelial cells, and lymphatic Endothelial cells. Each is linked with RRAGA in more than 1 cancer types. Because this analysis shows association rather than direction, both RRAGA-to-partner and partner-to-RRAGA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by RRAGA-low versus RRAGA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRAGA→partner) and Y-score (partner→RRAGA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Adipocytes →	+0.022	+1.700	<.001	.011	3	1
UCEC	Endothelial cells →	-0.032	-2.205	.023	.002	3	1
UCEC	lymphatic Endothelial cells →	-0.017	-1.866	.047	.016	3	1
UCEC	Neutrophils →	+0.013	+1.529	<.001	.022	3	1
UCEC	Basophils →	+0.137	+1.847	.028	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Adipocytes by RRAGA expression — UCEC

Explore this box plot interactively →