Q-omics provides the consensus-scored RPSAP74 profile across patient tissues and cancer cell-line models. RPSAP74 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in STAD. Among the 18 cancer types available for tumor–normal comparison, RPSAP74 is differentially expressed in 7, with the highest sampling consensus in COAD. Additionally, RPSAP74 RNA expression shows 8,909 significant protein co-abundance associations, with the highest sampling consensus in BRCA. Together, these results highlight STAD, COAD, and BRCA as cancer lineages where RPSAP74 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPSAP74 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPSAP74 survival associations across molecular data types. RPSAP74 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPSAP74 RNA expression–survival associations across cancer types. High RPSAP74 expression shows unfavorable associations in STAD, LIHC, ACC and PAAD, but favorable associations in KIRC and BLCA. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify STAD as the clearest survival context for RPSAP74 RNA expression.
This table summarizes RPSAP74 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for RPSAP74. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPSAP74 shows higher tumor expression in COAD, STAD, LUSC, LUAD, BLCA and KIRP. The COAD box plot shows higher RPSAP74 RNA expression in tumor versus normal tissue (log2 FC = +0.345, t-test p < 0.001).
This table shows molecular features associated with RPSAP74 in patient tissues and cancer cell lines. In patient samples, RPSAP74 shows the broadest associations at the RNA and protein expression levels, with BRCA recurring as the lineage with the largest associated feature set.
