RPSAP7

Across TCGA patient cohorts, RPSAP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,922 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RPSAP7-associated GO terms across cancer lineages are tRNA surveillance, rRNA metabolic process, and Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with RPSAP7 in more than 20 cancer types. Because this analysis shows association rather than direction, both RPSAP7-to-partner and partner-to-RPSAP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA surveillance grouped by RPSAP7-low versus RPSAP7-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPSAP7→partner) and Y-score (partner→RPSAP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	tRNA surveillance →	+0.063	+0.777	<.001	<.001	3	21
STAD	rRNA metabolic process →	+0.042	+0.086	<.001	<.001	3	20
UCS	Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.055	+0.409	.001	<.001	3	20
READ	Mitochondrial RNA 3'-end processing →	+0.047	+0.725	<.001	<.001	3	19
TGCT	XMP metabolic process →	+0.064	+0.804	<.001	<.001	3	19
MESO	5S class rRNA transcription by RNA polymerase III →	+0.054	+1.016	<.001	<.001	2	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,922 associations by consensus.

tRNA surveillance by RPSAP7 expression — UVM

Explore this box plot interactively →