RPSAP59

Across TCGA patient cohorts, RPSAP59 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,049 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RPSAP59-associated GO terms across cancer lineages are Establishment of protein localization to telomere, Establishment of protein localization to mitochondrial membrane, and Protein targeting to mitochondrion. Each is linked with RPSAP59 in more than 9 cancer types. Because this analysis shows association rather than direction, both RPSAP59-to-partner and partner-to-RPSAP59 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to telomere grouped by RPSAP59-low versus RPSAP59-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPSAP59→partner) and Y-score (partner→RPSAP59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Establishment of protein localization to telomere →	+0.066	+0.170	<.001	.001	3	10
ESCA	Establishment of protein localization to mitochondrial membrane →	+0.049	+0.137	<.001	.001	3	10
STAD	Protein targeting to mitochondrion →	+0.042	+0.071	<.001	<.001	3	10
ESCA	Oxidative phosphorylation →	+0.052	+0.100	<.001	<.001	3	10
ESCA	NADH dehydrogenase complex assembly →	+0.048	+0.099	<.001	<.001	3	10
ESCA	Cytoplasmic translation →	+0.074	+0.161	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,049 associations by consensus.

Establishment of protein localization to telomere by RPSAP59 expression — ESCA

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