RPSAP59

Across TCGA pan-cancer cohorts, RPSAP59 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RPSAP59 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RPSAP59 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPSAP59 expression acts as an unfavorable survival marker.

UVM, MESO, and LIHC are the cancer types where RPSAP59 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	III,IV	0.245	0.826	.001	72	view →
MESO	OS	Tertile	All	0.253	0.564	<.001	72	view →
LIHC	OS	Tertile	All	0.213	0.779	<.001	69	view →
BRCA	OS	Tertile	All	0.881	0.931	.011	39	view →
ACC	DFS	Tertile	All	0.048	0.623	<.001	27	view →
SKCM	OS	Tertile	II,III,IV	0.487	0.752	.003	24	view →
UCS	DFS	Tertile	All	0.143	0.461	.040	18	view →
LUSC	OS	Tertile	III,IV	0.135	0.713	.018	18	view →
KIRC	DFS	Tertile	III,IV	0.188	0.478	.037	12	view →
PAAD	OS	Tertile	All	0.240	0.593	.002	9	view →
OV	OS	Median	All	0.648	0.711	.045	4	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RPSAP59–UVM (OS)

Open the UVM breakdown →