RPSAP52

Across TCGA patient cohorts, RPSAP52 mutation is significantly associated with the RNA expression of many other genes, with 2,702 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPSAP52-associated genes across cancer lineages are C15orf40, TRMT10C, and WDR73. Each is linked with RPSAP52 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPSAP52-to-partner and partner-to-RPSAP52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C15orf40 grouped by RPSAP52-low versus RPSAP52-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPSAP52→partner) and Y-score (partner→RPSAP52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	C15orf40 →	+0.381	+3.340	.004	.005	3	2
SKCM	TRMT10C →	+0.633	+3.504	.009	.002	3	2
SKCM	WDR73 →	+0.447	+3.311	.001	.007	3	2
SKCM	SERHL2 →	+0.577	+3.360	<.001	.004	3	2
SKCM	TRAIP →	+0.573	+3.208	.004	.009	3	2
SKCM	RNU6-4P →	+0.305	+3.072	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,702 associations by consensus.

C15orf40 by RPSAP52 expression — SKCM

Explore this box plot interactively →