RPSAP51

Across TCGA pan-cancer cohorts, RPSAP51 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RPSAP51 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RPSAP51 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPSAP51 expression acts as an unfavorable survival marker, although some lineages such as HNSC and READ show a favorable association.

HNSC, KIRC, and READ are the cancer types where RPSAP51 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	III,IV	0.457	0.257	<.001	139	view →
KIRC	OS	Tertile	All	0.752	0.834	.001	95	view →
READ	DFS	Tertile	II,III,IV	1.000	0.399	.015	21	view →
UVM	OS	Tertile	III,IV	0.037	0.809	<.001	18	view →
UCEC	OS	Quartile	IV	0.937	0.641	.019	16	view →
LUSC	DFS	Quartile	III,IV	0.992	0.361	.017	14	view →
STAD	DFS	Tertile	All	0.343	0.517	.020	10	view →
THCA	DFS	Tertile	All	0.293	0.857	.048	6	view →
BRCA	OS	Tertile	II,III,IV	0.723	0.516	.036	4	view →
LGG	DFS	Quartile	All	0.280	0.437	.025	3	view →
LUAD	OS	Tertile	III,IV	0.600	0.219	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RPSAP51–HNSC (OS)

Open the HNSC breakdown →