Across TCGA pan-cancer cohorts, RPSAP51 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPSAP51’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RPSAP51 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPSAP51 is over-expressed in tumor, although a few such as LIHC show the opposite, repressed pattern.
KIRP, LUAD, and LUSC are the cancer types where RPSAP51 tumor–normal differential expression is most reproducible.