RPSAP5

Across TCGA pan-cancer cohorts, RPSAP5 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RPSAP5 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RPSAP5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPSAP5 expression acts as an unfavorable survival marker, although some lineages such as CESC and UVM show a favorable association.

LIHC, CESC, and UVM are the cancer types where RPSAP5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.590	0.772	<.001	70	view →
CESC	OS	Quartile	All	0.826	0.471	.001	58	view →
UVM	DFS	Quartile	All	0.803	0.409	.002	55	view →
KIRP	OS	Quartile	All	0.475	0.674	.003	40	view →
KICH	DFS	Quartile	III,IV	0.058	1.000	.002	32	view →
SARC	OS	Tertile	All	0.727	0.928	<.001	29	view →
ACC	DFS	Quartile	II,III,IV	0.206	0.859	.011	26	view →
UCS	OS	Tertile	IV	0.761	0.141	.024	24	view →
LUSC	DFS	Quartile	III,IV	0.452	0.778	.002	23	view →
THCA	OS	Median	All	1.000	0.843	.012	21	view →
MESO	DFS	Tertile	All	0.552	0.215	.019	12	view →
BRCA	OS	Tertile	IV	0.145	0.777	.014	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RPSAP5–LIHC (OS)

Open the LIHC breakdown →