RPSAP5

Across TCGA pan-cancer cohorts, RPSAP5 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RPSAP5’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where RPSAP5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPSAP5 is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.

LIHC, COAD, and HNSC are the cancer types where RPSAP5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPSAP5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	II,III,IV	+0.188	<.001	9	view →
COAD	Female	II,III,IV	+0.831	<.001	7	view →
HNSC	Male	All	+0.321	.004	5	view →
ESCA	Female	All	−0.786	.011	2	view →
PRAD	All	All	+0.131	.024	2	view →
KIRC	All	All	+0.105	.013	2	view →
READ	All	All	+0.278	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RPSAP5–LIHC

Open the LIHC breakdown →