RPSAP41

Across TCGA pan-cancer cohorts, RPSAP41 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPSAP41’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RPSAP41 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPSAP41 is over-expressed in tumor, although a few such as BRCA and READ show the opposite, repressed pattern.

LUSC, BRCA, and HNSC are the cancer types where RPSAP41 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPSAP41 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.164	<.001	4	view →
BRCA	Female	All	−0.093	.005	4	view →
HNSC	Male	II,III,IV	+0.076	.004	4	view →
READ	All	II,III,IV	−0.070	.031	3	view →
ESCA	All	II,III,IV	+0.404	.012	2	view →
UCEC	All	III,IV	−0.178	.049	2	view →
CHOL	All	All	+0.122	.015	1	view →
STAD	Male	II,III,IV	+0.096	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPSAP41–LUSC

Open the LUSC breakdown →