Q-omics provides the consensus-scored RPSAP41 profile across patient tissues and cancer cell-line models. RPSAP41 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, RPSAP41 is differentially expressed in 8, with the highest sampling consensus in LUSC. Additionally, RPSAP41 RNA expression shows 14,056 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight KIRC, LUSC, and UVM as cancer lineages where RPSAP41 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPSAP41 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPSAP41 survival associations across molecular data types. RPSAP41 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPSAP41 RNA expression–survival associations across cancer types. High RPSAP41 expression shows unfavorable associations in KIRC, UCEC, LIHC and ACC, but favorable associations in SKCM and THYM. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for RPSAP41 RNA expression.
This table summarizes RPSAP41 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for RPSAP41. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPSAP41 shows lower tumor expression in BRCA, READ and UCEC and higher tumor expression in LUSC, HNSC and ESCA. The LUSC box plot shows higher RPSAP41 RNA expression in tumor versus normal tissue (log2 FC = +0.164, t-test p < 0.001).
This table shows molecular features associated with RPSAP41 in patient tissues and cancer cell lines. In patient samples, RPSAP41 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
