RPSAP3

Across TCGA pan-cancer cohorts, RPSAP3 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RPSAP3 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RPSAP3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPSAP3 expression acts as an unfavorable survival marker, although some lineages such as SKCM and THCA show a favorable association.

LIHC, ACC, and SKCM are the cancer types where RPSAP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	II,III,IV	0.372	0.767	.001	57	view →
ACC	DFS	Tertile	All	0.167	0.749	.001	56	view →
SKCM	OS	Quartile	III,IV	0.828	0.586	.001	38	view →
THCA	OS	Quartile	All	0.975	0.871	.007	34	view →
OV	OS	Quartile	II,III,IV	0.641	0.718	.013	32	view →
COAD	DFS	Quartile	All	0.855	0.645	.008	23	view →
CESC	DFS	Quartile	II,III,IV	0.794	0.224	.005	22	view →
READ	OS	Median	II,III,IV	1.000	0.815	.007	22	view →
CHOL	OS	Quartile	All	1.000	0.485	.017	14	view →
KIRC	DFS	Quartile	IV	0.204	0.735	.004	14	view →
BRCA	OS	Tertile	III,IV	0.949	0.851	.002	13	view →
GBM	DFS	Quartile	All	0.376	0.174	.002	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RPSAP3–LIHC (OS)

Open the LIHC breakdown →