RPSAP3

Across TCGA pan-cancer cohorts, RPSAP3 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of RPSAP3’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPSAP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPSAP3 is over-expressed in tumor, although a few such as PAAD and HNSC show the opposite, repressed pattern.

COAD, LIHC, and THCA are the cancer types where RPSAP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPSAP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.472	<.001	10	view →
LIHC	All	II,III,IV	+0.167	<.001	6	view →
THCA	Female	II,III,IV	+0.266	.003	4	view →
KIRC	All	All	+0.077	.002	4	view →
KICH	Male	III,IV	+0.195	.003	3	view →
PAAD	Female	All	−0.384	.035	2	view →
CHOL	All	All	+0.301	.002	2	view →
HNSC	Female	All	−0.116	.037	2	view →
PRAD	All	All	+0.113	.041	2	view →
KIRP	All	All	+0.092	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

RPSAP3–COAD

Open the COAD breakdown →