RPS6P4

Across TCGA pan-cancer cohorts, RPS6P4 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RPS6P4 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RPS6P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPS6P4 expression acts as an unfavorable survival marker, although some lineages such as COAD show a favorable association.

UVM, KIRC, and UCS are the cancer types where RPS6P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	III,IV	0.075	0.814	<.001	36	view →
KIRC	OS	Tertile	All	0.712	0.891	<.001	36	view →
UCS	DFS	Tertile	All	0.156	0.537	.005	18	view →
LUSC	OS	Tertile	III,IV	0.079	0.803	<.001	18	view →
GBM	DFS	Tertile	All	0.105	0.255	.001	9	view →
SARC	OS	Tertile	All	0.655	0.845	.017	9	view →
READ	OS	Median	IV	0.455	0.824	.005	8	view →
COAD	DFS	Tertile	All	0.833	0.451	.025	6	view →
KICH	DFS	Tertile	All	0.425	0.847	.041	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RPS6P4–UVM (OS)

Open the UVM breakdown →