Across TCGA pan-cancer cohorts, RPS6P4 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RPS6P4’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where RPS6P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS6P4 is over-expressed in tumor.
COAD are the cancer types where RPS6P4 tumor–normal differential expression is most reproducible.