RPS6P12

Across TCGA pan-cancer cohorts, RPS6P12 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RPS6P12 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RPS6P12 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPS6P12 expression acts as an unfavorable survival marker, although some lineages such as LGG and CESC show a favorable association.

KIRC, SKCM, and KICH are the cancer types where RPS6P12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.771	0.896	<.001	152	view →
SKCM	OS	Quartile	II,III,IV	0.766	0.869	<.001	108	view →
KICH	DFS	Tertile	All	0.079	0.891	<.001	81	view →
CHOL	OS	Tertile	All	0.183	0.654	.001	54	view →
THCA	OS	Tertile	All	0.922	0.990	<.001	51	view →
LGG	DFS	Median	All	0.826	0.656	<.001	37	view →
ACC	DFS	Tertile	All	0.131	0.599	.002	36	view →
CESC	DFS	Tertile	IV	0.678	0.101	.009	30	view →
UVM	OS	Tertile	All	0.266	0.792	<.001	27	view →
READ	DFS	Tertile	IV	0.189	0.784	<.001	24	view →
KIRP	DFS	Tertile	II,III,IV	0.179	0.669	.044	18	view →
SARC	OS	Tertile	All	0.588	0.759	.022	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RPS6P12–KIRC (OS)

Open the KIRC breakdown →