RPS6KB2

Across TCGA patient cohorts, RPS6KB2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,559 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RPS6KB2-associated genes across cancer lineages are C17orf75, ZNF287, and AUH. Each is linked with RPS6KB2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RPS6KB2-to-partner and partner-to-RPS6KB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS6KB2 versus C17orf75 in HNSC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KB2→partner) and Y-score (partner→RPS6KB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	C17orf75 →	-0.621	-0.306	<.001	.002	3	4
HNSC	ZNF287 →	-0.448	-0.288	<.001	<.001	3	4
BRCA	AUH →	-0.464	-0.316	.001	.003	3	4
BRCA	NOSTRIN →	-0.869	-0.277	.006	.003	3	4
LSCC	ZBTB34 →	-0.401	-0.225	<.001	<.001	3	4
HNSC	PREPL →	-0.638	-0.325	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,559 associations by consensus.

RPS6KB2 vs C17orf75 — HNSC

Explore this scatter interactively →