RPS6KB1

Across TCGA patient cohorts, RPS6KB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,835 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPS6KB1-associated proteins across cancer lineages are VEZF1, LIG3, and BPTF. Each is linked with RPS6KB1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RPS6KB1-to-partner and partner-to-RPS6KB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS6KB1 versus VEZF1 in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KB1→partner) and Y-score (partner→RPS6KB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VEZF1 →	+0.385	+0.333	<.001	<.001	3	6
LSCC	LIG3 →	+0.416	+0.406	<.001	<.001	3	6
LSCC	BPTF →	+0.276	+0.455	<.001	<.001	3	6
LSCC	GTF3C4 →	+0.286	+0.324	<.001	<.001	3	5
BRCA	HEATR6 →	+0.376	+0.558	<.001	<.001	3	5
LSCC	SMG8 →	+0.229	+0.461	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,835 associations by consensus.

RPS6KB1 vs VEZF1 — GBM

Explore this scatter interactively →