RPS6KA6

Across TCGA cell cohorts, RPS6KA6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,159 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RPS6KA6-associated GO terms across cancer lineages are Regulation of mesoderm development, Establishment of vesicle localization, and Golgi to endosome transport. Each is linked with RPS6KA6 in more than 14 cancer types. Because this analysis shows association rather than direction, both RPS6KA6-to-partner and partner-to-RPS6KA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mesoderm development grouped by RPS6KA6-low versus RPS6KA6-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KA6→partner) and Y-score (partner→RPS6KA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of mesoderm development →	-0.645	-0.798	<.001	<.001	3	15
BREAST	Establishment of vesicle localization →	+0.048	+0.932	<.001	.006	3	7
BONE	Golgi to endosome transport →	+0.101	+1.388	.002	.003	3	6
SOFT_TISSUE	Protein localization to plasma membrane raft →	-0.111	-0.846	.006	.004	3	6
LUNG_SCLC	Detoxification of inorganic compound →	-0.176	-1.669	<.001	.002	3	6
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.106	+1.806	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,159 associations by consensus.

Regulation of mesoderm development by RPS6KA6 expression — OVARY

Explore this box plot interactively →