RPS6KA2

Across TCGA patient cohorts, RPS6KA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,357 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RPS6KA2-associated proteins across cancer lineages are NOP2, DPYSL2, and SORBS3. Each is linked with RPS6KA2 in more than 5 cancer types. Because this analysis shows association rather than direction, both RPS6KA2-to-partner and partner-to-RPS6KA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS6KA2 versus NOP2 in BRCA, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KA2→partner) and Y-score (partner→RPS6KA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NOP2 →	-0.373	-0.637	<.001	<.001	3	6
LSCC	DPYSL2 →	+0.378	+0.669	<.001	<.001	3	6
CCRCC	SORBS3 →	+0.362	+0.474	<.001	<.001	3	6
UCEC	MAP1A →	+0.518	+0.653	<.001	<.001	3	6
BRCA	YME1L1 →	-0.438	-0.880	<.001	<.001	3	6
HNSC	UTRN →	+0.310	+0.695	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,357 associations by consensus.

RPS6KA2 vs NOP2 — BRCA

Explore this scatter interactively →