RPS6KA2

Across TCGA patient cohorts, RPS6KA2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,608 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPS6KA2-associated genes across cancer lineages are SFTPC, LINC00710, and LDB3. Each is linked with RPS6KA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RPS6KA2-to-partner and partner-to-RPS6KA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS6KA2 versus SFTPC in LSCC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KA2→partner) and Y-score (partner→RPS6KA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SFTPC →	+2.800	+0.405	.003	.008	3	3
UCEC	LINC00710 →	+0.916	+0.596	<.001	<.001	3	3
GBM	LDB3 →	+0.848	+0.595	<.001	<.001	3	3
GBM	CDKL2 →	+0.938	+0.803	<.001	<.001	3	3
UCEC	PRDM8 →	+0.959	+0.798	<.001	<.001	3	3
UCEC	PLCXD3 →	+1.059	+0.650	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,608 associations by consensus.

RPS6KA2 vs SFTPC — LSCC

Explore this scatter interactively →