RPS6KA2

Across TCGA cell cohorts, RPS6KA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,713 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RPS6KA2-associated GO terms across cancer lineages are Endosomal transport, Regulation of intracellular transport, and Regulation of proteasomal protein catabolic process. Each is linked with RPS6KA2 in more than 11 cancer types. Because this analysis shows association rather than direction, both RPS6KA2-to-partner and partner-to-RPS6KA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by RPS6KA2-low versus RPS6KA2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KA2→partner) and Y-score (partner→RPS6KA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.060	+1.363	.001	.003	3	12
BONE	Regulation of intracellular transport →	+0.061	+1.733	<.001	.003	3	12
LUNG_SCLC	Regulation of proteasomal protein catabolic process →	+0.054	+1.619	<.001	<.001	3	11
SOFT_TISSUE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.091	+2.075	<.001	.001	3	11
BONE	Membrane biogenesis →	+0.111	+2.731	<.001	<.001	3	11
BONE	Vesicle-mediated transport to the plasma membrane →	+0.080	+2.583	.002	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,713 associations by consensus.

Endosomal transport by RPS6KA2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →