RPS6KA1

Across TCGA patient cohorts, RPS6KA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,184 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPS6KA1-associated proteins across cancer lineages are CAPZA1, ACSL5, and LDLRAP1. Each is linked with RPS6KA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RPS6KA1-to-partner and partner-to-RPS6KA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS6KA1 versus CAPZA1 in GBM, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6KA1→partner) and Y-score (partner→RPS6KA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CAPZA1 →	+0.290	+0.680	<.001	<.001	3	6
PDAC	ACSL5 →	+0.525	+0.356	.001	.001	2	6
GBM	LDLRAP1 →	+0.732	+0.732	<.001	<.001	3	5
COAD	MTHFR →	+0.847	+0.601	.003	.009	3	5
GBM	PTPN6 →	+0.696	+0.853	<.001	<.001	3	5
GBM	ICAM1 →	+0.694	+0.688	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,184 associations by consensus.

RPS6KA1 vs CAPZA1 — GBM

Explore this scatter interactively →