RPS6

Across TCGA cell cohorts, RPS6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,990 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RPS6-associated GO terms across cancer lineages are tRNA surveillance, snRNA catabolic process, and CUT catabolic process. Each is linked with RPS6 in more than 11 cancer types. Because this analysis shows association rather than direction, both RPS6-to-partner and partner-to-RPS6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA surveillance grouped by RPS6-low versus RPS6-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS6→partner) and Y-score (partner→RPS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	tRNA surveillance →	+0.082	+0.592	.006	.007	2	12
LUNG_SCLC	snRNA catabolic process →	+0.125	+0.743	<.001	<.001	3	11
LUNG_SCLC	CUT catabolic process →	+0.113	+0.711	<.001	.001	3	10
STOMACH	Positive regulation of neutrophil activation →	+0.913	+0.991	.002	.005	2	10
STOMACH	Symbiont entry into host →	-0.083	-0.955	.001	<.001	3	9
STOMACH	Symbiont entry into host cell →	-0.083	-0.955	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,990 associations by consensus.

tRNA surveillance by RPS6 expression — LUNG_SCLC

Explore this box plot interactively →