RPS5

Across TCGA pan-cancer cohorts, RPS5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RPS5 data layer compared with 20 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RPS5 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RPS5 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, HNSC, and CCRCC are the cancer types where RPS5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	1.000	0.409	.016	12	view →
HNSC	DFS	Quartile	II,III,IV	1.000	0.911	.017	6	view →
CCRCC	OS	Quartile	All	0.739	0.923	.012	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RPS5–UCEC (DFS)

Open the UCEC breakdown →