RPS5

Across TCGA patient cohorts, RPS5 mutation is significantly associated with the RNA expression of many other genes, with 64 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPS5-associated genes across cancer lineages are RNU6-129P, MIR5591, and MIR4301. Each is linked with RPS5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS5-to-partner and partner-to-RPS5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-129P grouped by RPS5-low versus RPS5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS5→partner) and Y-score (partner→RPS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-129P →	+0.170	+4.566	<.001	.003	3	2
UCEC	MIR5591 →	+0.236	+4.300	<.001	.005	3	1
UCEC	MIR4301 →	+0.231	+4.566	<.001	.003	3	1
CESC	OR2AI1P →	+0.063	+5.669	<.001	.003	3	1
CESC	ANOS2P →	+0.022	+5.539	<.001	.004	3	1
CESC	LINC00293 →	+0.025	+5.418	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

RNU6-129P by RPS5 expression — UCEC

Explore this box plot interactively →