RPS4Y1

Across TCGA cell cohorts, RPS4Y1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,341 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible RPS4Y1-associated GO terms across cancer lineages are Regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway, UDP biosynthetic process, and Pyrimidine ribonucleoside diphosphate biosynthetic process. Each is linked with RPS4Y1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RPS4Y1-to-partner and partner-to-RPS4Y1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway grouped by RPS4Y1-low versus RPS4Y1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS4Y1→partner) and Y-score (partner→RPS4Y1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway →	+0.121	+4.024	.007	.001	2	6
KIDNEY	UDP biosynthetic process →	-0.080	-4.074	.002	.002	3	5
KIDNEY	Pyrimidine ribonucleoside diphosphate biosynthetic process →	-0.080	-4.074	.002	.002	3	5
OVARY	DNA repair-dependent chromatin remodeling →	+0.087	+0.521	<.001	<.001	3	5
OVARY	Schwann cell differentiation →	+0.109	+0.361	<.001	<.001	3	4
CNS	Negative regulation of toll-like receptor signaling pathway →	+0.065	+3.350	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,341 associations by consensus.

Regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway by RPS4Y1 expression — CNS

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