Across TCGA patient cohorts, RPS4XP21 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPS4XP21-associated genes across cancer lineages are MIR98, OR5B2, and CA15P2. Each is linked with RPS4XP21 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS4XP21-to-partner and partner-to-RPS4XP21 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS4XP21→partner) and Y-score (partner→RPS4XP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR98 →	+0.645	+3.801	<.001	.004	3	1
UCEC	OR5B2 →	+0.126	+4.551	<.001	.001	3	1
SKCM	CA15P2 →	+0.038	+5.469	<.001	.002	3	1
UCEC	MIR378E →	+0.608	+4.453	<.001	.006	3	1
UCEC	FTMT →	+0.223	+3.434	.007	.006	3	1
UCEC	RNU6-1292P →	+0.591	+4.453	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

RPS4XP21 survival (RNA) · tumor vs normal (RNA) · all RPS4XP21 data types