RPS4XP11

Across TCGA pan-cancer cohorts, RPS4XP11 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RPS4XP11 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RPS4XP11 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPS4XP11 expression acts as an unfavorable survival marker, although some lineages such as CESC and LUSC show a favorable association.

LUAD, CESC, and LUSC are the cancer types where RPS4XP11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.466	0.642	<.001	89	view →
CESC	DFS	Quartile	All	0.733	0.306	<.001	82	view →
LUSC	OS	Quartile	All	0.525	0.337	.002	38	view →
BLCA	DFS	Tertile	II,III,IV	0.589	0.437	.005	35	view →
KIRP	DFS	Tertile	All	0.868	0.963	.010	30	view →
SARC	OS	Median	All	0.400	0.611	<.001	29	view →
ACC	DFS	Median	All	0.514	0.801	.001	26	view →
LIHC	DFS	Median	II,III,IV	0.217	0.433	.009	22	view →
COAD	OS	Quartile	IV	0.387	0.790	.011	21	view →
SKCM	OS	Tertile	II,III,IV	0.936	0.787	.007	16	view →
KICH	DFS	Quartile	III,IV	0.047	1.000	.010	13	view →
UCS	OS	Quartile	II,III,IV	0.517	0.937	.008	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RPS4XP11–LUAD (OS)

Open the LUAD breakdown →