RPS4XP11

Across TCGA pan-cancer cohorts, RPS4XP11 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of RPS4XP11’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPS4XP11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS4XP11 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

KIRC, THCA, and COAD are the cancer types where RPS4XP11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS4XP11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.251	<.001	9	view →
THCA	All	II,III,IV	+0.589	<.001	8	view →
COAD	All	II,III,IV	+0.394	.001	7	view →
LUAD	All	All	+0.314	<.001	7	view →
UCEC	All	All	−0.517	.011	6	view →
CHOL	All	All	+0.374	.002	4	view →
BRCA	Female	II,III,IV	−0.173	.020	4	view →
KICH	Male	All	+0.380	.007	3	view →
LIHC	All	All	+0.127	.017	2	view →
STAD	Male	IV	+0.690	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

RPS4XP11–KIRC

Open the KIRC breakdown →