Across TCGA pan-cancer cohorts, RPS3AP54 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated RPS3AP54 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RPS3AP54 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPS3AP54 expression acts as an unfavorable survival marker, although some lineages such as GBM and READ show a favorable association.

KICH, UCEC, and THCA are the cancer types where RPS3AP54 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.508	0.895	<.001	108	view →
UCEC	DFS	Tertile	All	0.784	0.879	.001	78	view →
THCA	DFS	Tertile	III,IV	0.797	0.929	<.001	52	view →
CESC	OS	Quartile	All	0.789	0.908	.001	50	view →
MESO	DFS	Median	III,IV	0.285	0.489	.007	39	view →
STAD	DFS	Tertile	All	0.252	0.483	.009	26	view →
LUSC	DFS	Median	II,III,IV	0.521	0.792	.012	21	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
UVM	OS	Tertile	II,III,IV	0.218	0.712	.016	18	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	15	view →
KIRC	DFS	Median	IV	0.539	0.678	.026	14	view →
SKCM	DFS	Median	IV	0.111	0.694	.004	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

Exploration

Same gene, other analysis: RPS3AP54 tumor-vs-normal RNA expression · all RPS3AP54 data types