Across TCGA pan-cancer cohorts, RPS3AP54 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RPS3AP54’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where RPS3AP54 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS3AP54 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.
THCA, LIHC, and UCEC are the cancer types where RPS3AP54 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS3AP54 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.