RPS3AP48

Across TCGA pan-cancer cohorts, RPS3AP48 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RPS3AP48 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RPS3AP48 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPS3AP48 expression acts as an unfavorable survival marker, although some lineages such as THCA and CESC show a favorable association.

OV, THCA, and ACC are the cancer types where RPS3AP48 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Tertile	All	0.294	0.415	.005	78	view →
THCA	DFS	Tertile	All	0.946	0.774	.001	57	view →
ACC	DFS	Quartile	II,III,IV	0.306	0.602	.005	46	view →
CESC	OS	Tertile	All	0.703	0.510	.010	40	view →
COAD	DFS	Quartile	All	0.790	0.659	.012	23	view →
UCEC	OS	Tertile	All	0.511	0.743	.005	20	view →
DLBC	DFS	Quartile	III,IV	0.150	0.771	.011	19	view →
LIHC	DFS	Tertile	II,III,IV	0.220	0.513	.002	18	view →
SKCM	OS	Quartile	All	0.428	0.267	.005	15	view →
ESCA	OS	Median	IV	0.698	0.222	.006	13	view →
TGCT	DFS	Tertile	III,IV	0.604	1.000	.044	12	view →
PAAD	OS	Quartile	II,III,IV	0.797	0.556	.017	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RPS3AP48–OV (OS)

Open the OV breakdown →