Q-omics provides the consensus-scored RPS3AP34 profile across patient tissues and cancer cell-line models. RPS3AP34 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in SKCM. Among the 18 cancer types available for tumor–normal comparison, RPS3AP34 is differentially expressed in 8, with the highest sampling consensus in LUSC. Additionally, RPS3AP34 RNA expression shows 18,286 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight SKCM, LUSC, and THYM as cancer lineages where RPS3AP34 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPS3AP34 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPS3AP34 survival associations across molecular data types. RPS3AP34 RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPS3AP34 RNA expression–survival associations across cancer types. High RPS3AP34 expression shows favorable associations in SKCM, BLCA, LAML, BRCA, CESC and HNSC. The SKCM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify SKCM as the clearest survival context for RPS3AP34 RNA expression.
This table summarizes RPS3AP34 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for RPS3AP34. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPS3AP34 shows lower tumor expression in LUSC, LUAD, KICH, BRCA and THCA and higher tumor expression in CHOL. The LUSC box plot shows higher RPS3AP34 RNA expression in normal versus tumor tissue (log2 FC = −0.945, t-test p < 0.001).
This table shows molecular features associated with RPS3AP34 in patient tissues and cancer cell lines. In patient samples, RPS3AP34 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
