RPS3AP11

Across TCGA patient cohorts, RPS3AP11 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPS3AP11-associated genes across cancer lineages are TRIM49C, RNU6-136P, and MIR550A1. Each is linked with RPS3AP11 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS3AP11-to-partner and partner-to-RPS3AP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM49C grouped by RPS3AP11-low versus RPS3AP11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS3AP11→partner) and Y-score (partner→RPS3AP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRIM49C →	+0.543	+4.233	<.001	.009	3	1
UCEC	RNU6-136P →	+0.628	+4.188	.005	.009	3	1
UCEC	MIR550A1 →	+0.622	+5.184	.002	.001	3	1
UCEC	RNU6-644P →	+0.691	+5.567	<.001	<.001	3	1
UCEC	RNU6-1077P →	+0.817	+4.188	<.001	.009	3	1
UCEC	HMGB1P12 →	+0.188	+4.578	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

TRIM49C by RPS3AP11 expression — UCEC

Explore this box plot interactively →