RPS27AP19

Across TCGA pan-cancer cohorts, RPS27AP19 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPS27AP19’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPS27AP19 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS27AP19 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, COAD, and UCEC are the cancer types where RPS27AP19 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS27AP19 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.212	<.001	6	view →
COAD	All	All	+0.204	.019	4	view →
UCEC	All	IV	+0.305	.031	2	view →
THCA	All	All	−0.164	.001	2	view →
LIHC	All	All	+0.059	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RPS27AP19–KIRC

Open the KIRC breakdown →